Having done both the 10man and 25man version vs 2 drakes I can say for sure it's a lot rougher in the 10 man. You simply don't have the luxury of brining 3 tanks, and don't have extra healers to spread around for portals. Also, the damage the tanks take is not much less than the 25man, and you only have 1/3rd the healers, making their job rough.
The strategy we used was quite different than anything I've seen in any other videos. Basically, instead of having an off tank on the drakes, we had one tank hold both the dragon and the drakes. Also shown from the tanks view.
Priest healer (disc)
Hunter x2 (MM and BM)
Warrior DPS (arms)